What!?

[theendofanera]

http://uk.news.yahoo.com/afp/2007101...37b0eca_1.html

[FloridaNative]

So the patient survived and the doctors and nurses could have an after work party to celebrate it! Looks like a win win to me!

[Distantshore]

I never even knew they used alcohol to reverse the effects of ethylene glycol.
Interesting!

[luvuvibanez]

An occupation in the medical field sounds a bit more fun now.

[Dino]

Next time my cat comes home sick I'll know what to do! Thanks!

[LonePhantom]

Good old outside of the box thinking from Australians, and it worked too!

[sihackett29]

For anyone who's interested ethylene glycol is metabolised by an enzyme in the liver called alcohol dehydrogenase (same one that metabolises alcohol) to form glycoaldehyde. Through interaction with another enzyme, aldehyde dehydrogenase, ethylene glycol is then metabolized to glycolic acid (GA). A profound acidosis (blood turning acidic) occurs.
Because ethanol is the preferential target for alcohol dehydrogenase, the presence of ethanol may essentially block metabolism of ethylene glycol so the toxic effects of the byproduct of the metabolism are not formed. Clever eh?
Although why the clinic used vodka I'm not so sure, infact, anotherdrug called 4-MP is the preferential treatment! must have been out inthe sticks

[David McCarroll]

Originally Posted by sihackett29

For anyone who's interested ethylene glycol is metabolised by an enzyme in the liver called alcohol dehydrogenase (same one that metabolises alcohol) to form glycoaldehyde. Through interaction with another enzyme, aldehyde dehydrogenase, ethylene glycol is then metabolized to glycolic acid (GA). A profound acidosis (blood turning acidic) occurs.
Because ethanol is the preferential target for alcohol dehydrogenase, the presence of ethanol may essentially block metabolism of ethylene glycol so the toxic effects of the byproduct of the metabolism are not formed. Clever eh?
Although why the clinic used vodka I'm not so sure, infact, anotherdrug called 4-MP is the preferential treatment! must have been out inthe sticks

Mackay is the armpit of the sticks......

[Distantshore]

Originally Posted by sihackett29

For anyone who's interested ethylene glycol is metabolised by an enzyme in the liver called alcohol dehydrogenase (same one that metabolises alcohol) to form glycoaldehyde. Through interaction with another enzyme, aldehyde dehydrogenase, ethylene glycol is then metabolized to glycolic acid (GA). A profound acidosis (blood turning acidic) occurs.
Because ethanol is the preferential target for alcohol dehydrogenase, the presence of ethanol may essentially block metabolism of ethylene glycol so the toxic effects of the byproduct of the metabolism are not formed. Clever eh?
Although why the clinic used vodka I'm not so sure, infact, anotherdrug called 4-MP is the preferential treatment! must have been out inthe sticks

Cool! Good stuff!

[theendofanera]

Originally Posted by sihackett29

For anyone who's interested ethylene glycol is metabolised by an enzyme in the liver called alcohol dehydrogenase (same one that metabolises alcohol) to form glycoaldehyde. Through interaction with another enzyme, aldehyde dehydrogenase, ethylene glycol is then metabolized to glycolic acid (GA). A profound acidosis (blood turning acidic) occurs.
Because ethanol is the preferential target for alcohol dehydrogenase, the presence of ethanol may essentially block metabolism of ethylene glycol so the toxic effects of the byproduct of the metabolism are not formed. Clever eh?
Although why the clinic used vodka I'm not so sure, infact, anotherdrug called 4-MP is the preferential treatment! must have been out inthe sticks

Nice one, didnt know that.
Thanks

[DavyH]

Originally Posted by sihackett29

For anyone who's interested ethylene glycol is metabolised by an enzyme in the liver called alcohol dehydrogenase (same one that metabolises alcohol) to form glycoaldehyde. Through interaction with another enzyme, aldehyde dehydrogenase, ethylene glycol is then metabolized to glycolic acid (GA). A profound acidosis (blood turning acidic) occurs.
Because ethanol is the preferential target for alcohol dehydrogenase, the presence of ethanol may essentially block metabolism of ethylene glycol so the toxic effects of the byproduct of the metabolism are not formed. Clever eh?
Although why the clinic used vodka I'm not so sure, infact, anotherdrug called 4-MP is the preferential treatment! must have been out inthe sticks

The things you can learn on a guitarists' website. Excellent! It's amazing the depth of knowledge in a fairly small community.

Next question: what subject does no Jemsiter know anything about? (except maybe thrift/resisting GAS)

[Distantshore]

Originally Posted by DavyH

The things you can learn on a guitarists' website. Excellent! It's amazing the depth of knowledge in a fairly small community.

Next question: what subject does no Jemsiter know anything about? (except maybe thrift/resisting GAS)

Right