REALLY COMES DOWN TO PREFERENCE REALLY. NO GUITAR PLAYS BETTER. I HAVE SEEN SOME GUITARIST USING A FREAKING CHIBANEZ AND THEY CAN MAKE IT SOUND LIKE HEAVEN.
That's a completely off-topic, irrelevant point. I struggle to see why it's in the thread, along with the other, similar comments.
Some guitars do play 'better' than others. Whether the Chibanez guy sounds amazing or not has nothing to so with the quality of the guitar.
The best racer in the world could probably outrace me on a difficult track in an old Fiesta even if I was driving a Ferrari. However, the Ferrari is still demostrably better than the Fiesta.
Vai could play better on a Squier Strat than I could on a JEM, but the JEM is still a better guitar.
The OP is asking which guitars 'play' better - i.e. feel slicker, set up more easily, sound superior, are better quality, etc etc.
"NO GUITAR PLAYS BETTER" is a ridiculous statement. A Jem WILL play better than a Squier, all things being the same.