read the articles relevant to setting up a floating trem either on jemsite or ibanezrules - basically your trem is balanced between the tension of the strings and the extension of the
trem springs.
less
string tension (like drop D) means that the balance is not equal - as fettouhi says - you need to rebalance if you want to de-tune and do it again if you ever want to go back to eadgbe tuning !