Sounds like the nut has slided a bit; is it tight? If the low E is far in on the fretboard, then it should be a string misalignment at the bridge, nut, or both.
That said, all RGs I've played have the high E pretty close to the edge of the fretboard. The upside is, when you tap and the string comes off the fretboard you can get pretty cool effects (and that's without a
whammy pedal 
)