I wouldn't change anything until i'd played it for at least a couple of weeks.
For that '80s sound, i'd go for a
Duncan Distortion or JB in the bridge, or maybe a
DiMarzio Super Distortion. But the big factor in that sound is also the "modded Marshall" amp tone that everybody was using back then.
I believe Gotoh locking tuners should be a direct fit to replace the stock Ibanez ones. I'm not sure if you'll need to change the bridge... i guess it depends on how hard you are on the trem and what kind of tuning stability you're getting vs. your expectations.
Try it for a while first, then mod to your heart's desire!