Well, at the risk of sounding flippant, it makes more sense to have a
Strat style hard tail bridge, as the Tune-O-Matic really is designed for a guitar with a pretty substantial
neck angle - never could really comprehend the sense in sinking it into the body, and if you angle the neck pocket, you'll end up with the pickups sticking half an inch out of the face of the guitar. I am merely speculating, but I think you'll get more tone and sustain out of a Strat style bridge and string through style setup than a Tune-O-Matic in any case.