With AANJ you can't do that at all, on a Jackson you don't need to do it - DX series have
reversed headstock and ESP MII have reversed headstock as well.
It'll work on Fender as long as you use a strat neck on a strat (tele neck won't fit on a strat) but you'll need to pull the nut and install it backwards or just cut a new nut.
What guitar do you want to do this to and why?
ilia
P.S. Lefthanded
locking nuts can be bought.