Easily possible, Jing. You just need to match up Ohms, and most amps provide two options, one tailored to two 4x12's, the otherfor one 4x12.
Never played a Laney myself, so I can't give you advice, but the guys from Opeth have gotten some VERY heavy sounds from what I've always been told is a medium gain amp, so let's say they're probably versatile enough for you to get whatever you're looking for.
