Dude, I have a nomad 45, and being my first
tube amp i've had teething problems.
I would seriously recommend changing the pre-amp tube, and problem with tone I find comes in the form of pre-tube trouble, and volume and power in power-tube probs.
In the mesa nomads the very first tube (the one behind the power transformer) is a universal tube that is the initial tube that the signal always goes through. Cause normally depending on which channel you're using diferent tubes are used, but this first one is always used.
I find this tube to be the problem one and I always check that one first when the tone starts going funky. Infact I had to do it last night. I stupidly left my amp in standby overnight

retard me. And it cained that first pre-amp tube. So the tone was starting to get brittle. Swapped it over and back to loveley singing mesa tone.
The other way you can tell this is if the problem is happening over all the channels. If you're having global tone trouble then again this is likley to be the problem. I've yet to have a channel tube go (TOUCH WOOD!) but i've replaced that first tube twice.
Anyway hope this may help. If not give mesa a ring they are helpful and friendly. Oh and if you're having switching trouble - make sure the FS is plugged in securley...ermm again silly me doesn't check these things and i looked a total fool at the store when i took it back saying man my channel switching is screwed. Turned out it wasn't pluged in right!
Again good luck with this let us know how you get on,
Dontlet it deter you fmo the nomads they ROCK N RULE!
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