here's my experience, which may halp a little. *i replaced the Blaze II in one of my 540S7s with a Duncan Custom, which is a high but not super high
output pickup that works well in mahogany body guitars like LPs and SGs. *the Duncan added a little bit extra edge but a lot more clarity and articulation - i am very happy with it. *for reference, i play high gain metal with occasional clean parts and rare medium distorted parts.
i changed both of my RG7620
bridge pickups to Duncan JBs. *i didn't mind the tone of the New 7, but the JB had more sizzle and clarity.
hopefully that helps some?!? *i don't know DiMarzio models as well as i know Duncans.