Dreamweaver is also my choice and if your hard code is up to speed Hotdog Pro is a reasonable alternative.
You can never go wrong with CuteFTP, it's stood the test of time and is free.
Photoshop and PSP6 are my two design faves and also a little program called universe which lets you create fantastic backgrounds of...you guessed it...universe's

i.e. star fields, gas clouds, vortex's, nebula's etc...
You can find a demo here and it's quite small :
http://www.diardsoftware.com/
gl
Steve