As with any other pickup it really depends on what you're pumping it through. While I can say TTZ is a pretty
versatile pickup, for Satch and Vai type stuff I can think of others that would do the job better. A good compromise between heavy chord driven rock and lyrical type lead work while used in a basswood axe would be a
Dimarzio Norton in the bridge slot.
Again, it depends on what you're pumping it through, and what your interpretation of instrumental rock is.
Mike