What!? - Jemsite
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post #1 of 12 (permalink) Old 10-10-2007, 08:54 AM Thread Starter
 
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post #2 of 12 (permalink) Old 10-10-2007, 09:45 AM
 
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Re: What!?

So the patient survived and the doctors and nurses could have an after work party to celebrate it! Looks like a win win to me!
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post #3 of 12 (permalink) Old 10-10-2007, 02:54 PM
 
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Re: What!?

I never even knew they used alcohol to reverse the effects of ethylene glycol.
Interesting!
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post #4 of 12 (permalink) Old 10-10-2007, 03:38 PM
 
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Re: What!?

An occupation in the medical field sounds a bit more fun now.
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post #5 of 12 (permalink) Old 10-10-2007, 03:41 PM
 
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Re: What!?

Next time my cat comes home sick I'll know what to do! Thanks!
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post #6 of 12 (permalink) Old 10-10-2007, 06:10 PM
 
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Re: What!?

Good old outside of the box thinking from Australians, and it worked too!
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post #7 of 12 (permalink) Old 10-10-2007, 06:38 PM
 
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Re: What!?

For anyone who's interested ethylene glycol is metabolised by an enzyme in the liver called alcohol dehydrogenase (same one that metabolises alcohol) to form glycoaldehyde. Through interaction with another enzyme, aldehyde dehydrogenase, ethylene glycol is then metabolized to glycolic acid (GA). A profound acidosis (blood turning acidic) occurs.
Because ethanol is the preferential target for alcohol dehydrogenase, the presence of ethanol may essentially block metabolism of ethylene glycol so the toxic effects of the byproduct of the metabolism are not formed. Clever eh?
Although why the clinic used vodka I'm not so sure, infact, anotherdrug called 4-MP is the preferential treatment! must have been out inthe sticks
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post #8 of 12 (permalink) Old 10-10-2007, 06:55 PM
 
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Re: What!?

Quote:
Originally Posted by sihackett29 View Post
For anyone who's interested ethylene glycol is metabolised by an enzyme in the liver called alcohol dehydrogenase (same one that metabolises alcohol) to form glycoaldehyde. Through interaction with another enzyme, aldehyde dehydrogenase, ethylene glycol is then metabolized to glycolic acid (GA). A profound acidosis (blood turning acidic) occurs.
Because ethanol is the preferential target for alcohol dehydrogenase, the presence of ethanol may essentially block metabolism of ethylene glycol so the toxic effects of the byproduct of the metabolism are not formed. Clever eh?
Although why the clinic used vodka I'm not so sure, infact, anotherdrug called 4-MP is the preferential treatment! must have been out inthe sticks

Mackay is the armpit of the sticks......
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post #9 of 12 (permalink) Old 10-10-2007, 08:12 PM
 
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Re: What!?

Quote:
Originally Posted by sihackett29 View Post
For anyone who's interested ethylene glycol is metabolised by an enzyme in the liver called alcohol dehydrogenase (same one that metabolises alcohol) to form glycoaldehyde. Through interaction with another enzyme, aldehyde dehydrogenase, ethylene glycol is then metabolized to glycolic acid (GA). A profound acidosis (blood turning acidic) occurs.
Because ethanol is the preferential target for alcohol dehydrogenase, the presence of ethanol may essentially block metabolism of ethylene glycol so the toxic effects of the byproduct of the metabolism are not formed. Clever eh?
Although why the clinic used vodka I'm not so sure, infact, anotherdrug called 4-MP is the preferential treatment! must have been out inthe sticks
Cool! Good stuff!
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post #10 of 12 (permalink) Old 10-11-2007, 07:37 AM Thread Starter
 
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Re: What!?

Quote:
Originally Posted by sihackett29 View Post
For anyone who's interested ethylene glycol is metabolised by an enzyme in the liver called alcohol dehydrogenase (same one that metabolises alcohol) to form glycoaldehyde. Through interaction with another enzyme, aldehyde dehydrogenase, ethylene glycol is then metabolized to glycolic acid (GA). A profound acidosis (blood turning acidic) occurs.
Because ethanol is the preferential target for alcohol dehydrogenase, the presence of ethanol may essentially block metabolism of ethylene glycol so the toxic effects of the byproduct of the metabolism are not formed. Clever eh?
Although why the clinic used vodka I'm not so sure, infact, anotherdrug called 4-MP is the preferential treatment! must have been out inthe sticks
Nice one, didnt know that.
Thanks
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post #11 of 12 (permalink) Old 10-12-2007, 01:11 AM
 
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Re: What!?

Quote:
Originally Posted by sihackett29 View Post
For anyone who's interested ethylene glycol is metabolised by an enzyme in the liver called alcohol dehydrogenase (same one that metabolises alcohol) to form glycoaldehyde. Through interaction with another enzyme, aldehyde dehydrogenase, ethylene glycol is then metabolized to glycolic acid (GA). A profound acidosis (blood turning acidic) occurs.
Because ethanol is the preferential target for alcohol dehydrogenase, the presence of ethanol may essentially block metabolism of ethylene glycol so the toxic effects of the byproduct of the metabolism are not formed. Clever eh?
Although why the clinic used vodka I'm not so sure, infact, anotherdrug called 4-MP is the preferential treatment! must have been out inthe sticks
The things you can learn on a guitarists' website. Excellent! It's amazing the depth of knowledge in a fairly small community.

Next question: what subject does no Jemsiter know anything about? (except maybe thrift/resisting GAS)
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post #12 of 12 (permalink) Old 10-12-2007, 01:26 AM
 
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Re: What!?

Quote:
Originally Posted by DavyH View Post
The things you can learn on a guitarists' website. Excellent! It's amazing the depth of knowledge in a fairly small community.

Next question: what subject does no Jemsiter know anything about? (except maybe thrift/resisting GAS)
Right
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