Join Date: Feb 2005
Location: Wirral, England
For anyone who's interested ethylene glycol is metabolised by an enzyme in the liver called alcohol dehydrogenase (same one that metabolises alcohol) to form glycoaldehyde. Through interaction with another enzyme, aldehyde dehydrogenase, ethylene glycol is then metabolized to glycolic acid (GA). A profound acidosis (blood turning acidic) occurs.
Because ethanol is the preferential target for alcohol dehydrogenase, the presence of ethanol may essentially block metabolism of ethylene glycol so the toxic effects of the byproduct of the metabolism are not formed. Clever eh?
Although why the clinic used vodka I'm not so sure, infact, anotherdrug called 4-MP is the preferential treatment! must have been out inthe sticks