I don't have one myself, but a friend has an RG 370 with and Edge Pro II and while not the greatest, it stays in tune pretty well.
Pull it up and it has the double-neutral problem, but a quick push down and it's back in tune.
The fix Rich is using costs (I think) about $30 from his site, if you buy the guitar from him. He has a great reputation and I'll be buying an RG 1550 (with the fix) from him very soon. (I know I've been saying that for a year, but things are finally looking up :-) )
It actually depends on the guitar, I've heard of some that stay in tune perfectly with the 'new' studs and others that will go VERY sharp on pull-up.
As to damaging the wood, what Rich says is true, after about 10 years of abuse it could very well oval the holes on a basswood body, from the studs rocking in the anchors, but there are PLENTY of guitars out there that have OFR trems with no locking studs, made from various types of wood that are as old as this style of trem itself that are still playing just fine. So I'd say don't worry about it until it happens, and even if it does it's not very difficult to fix.
Another friend has an old American Standard Strat, from when they first put in the two point trems with the "String Saver" type saddles and his guitar is still just fine.
Granted you can't do "Vai-olent" tremming with that kind of bridge, but he goes "Hendrix" on it just about every day, and Jimi was no kitten with a whammy bar.
But as always when it comes to wood, YMMV.
If you're not buying from Rich, try the guitar you're thinking about buying, bring a tuner, ask the salesman to let you properly tune the guitar (even if it's not set up just right) and do some dives and pulls.
Can you live with it's performance?
Is the performance good? Bad? Ugly?
If the trem won't stay in tune but you're in love with the rest of the guitar, call Rich, he'll fix you up . . . it's cheap . . . easy . . . and it works.
If you're spending this much on the guitar already (you are aware of how much Jems cost right?
) what's another thirty-something dollars for new studs and the "fix"?
Of course there are those that argue that you shouldn't have to spend more, but I'll re-type my car example . . .
I bought a Thunderbird with the crappy Motorolla radio . . . knowing I was going to replace it almost before I got the car into my own driveway . . . did that bother me? Nope, I just went and got a new radio.
Many MANY people buy RG's and change the pickups . . . why? They don't like the stock ones . . . granted the studs are a problem, not a preferance, but since Ibanez doesn't see them as a problem, guess what? It's NOT a problem . . . such is life.