"Better" is totally subjective, so whether you prefer the neck pickup sound better on a 21/2 or 24 fret model is up to you. For notes up to the 12th fret, a 22 fretter neck pickup will give a little more bass, since it's nearer the center point of the string - all else being equal. But all else usually ISN'T equal, so again, what sounds best to you, vs. do you need 24 fets?
I prefer 22 frets for many reasons, few of which have to do with notes or sound.
1) I learned on 22 fret Fender & Kramer guitars
2) I rarely play that high anyway, and if I need 4 whole 8ves, that's what bending and whammy bars are for.
3) I do slightly prefer that stratty position 2 sound and neck bucker sounds from a 22 freter...I think.
4) like the greater space between my H-S-H pickps on a 22 fretter; dunno why.
5) I love the JS
/Radius body and they don't make 'em in 24 fret versions.
You pays your money and takes your choice..