I’ve been debating between the RG1550 for the RG1570. Given that I’m left-handed it minimizes my options. Right-handed versions are no different then the Left-handed so if you use a right-handed version your opinions are just a valid.

Other then the obvious (Pick-guard) what are the major differences, and are they significant enough to sway your decision of which is the best value for the money?

best bet is to play them both.

Holy unnecessary font size, Batman!!!

There isn't really a difference other than the pickguard!

However, it's not just a cosmetic difference, The extra couple of mm thickness of the pickguard alters your playing position slightly so with the 50 your hand sits marginally closer to the strings. But within a few minutes of playing either (even alternating between the two, you get used to the one your playing easily

So just choose whichever one you like the look of

... either way, they should be great.
My personal preference: w/pickguard

ps:
since you're in CA, i might have a lead for a 550DY in lefty

Reg

Comes down to whether you like pickguards and maple fretboards imho.

I have a 1570 and it's a great guitar, but I prefer maple fretboards to rosewood, and love bright colours, so I would go for the 1550 poisoned pumpkin.

Rock on!

I prefer the maple fretboards also but my Fender Strat has maple so I thought the RG1570 rosewood would make for a change....

I kind'a figured there wasn't any significant difference but I wanted to make sure. Besides I can always by an aftermarket pickguard.....

i'm eyeing this guitar also and feel the same way. let me know what you decide!