Go take a look at the American Special Strat, I like the neck on these more than the American Standard. They come with jumbo frets, instead of the medium jumbo and it has the 70's style head stock. The pickup on the American Standard 2012 now comes with Custom Shop 50's. The trem on the Am. Standard is better than the Am. Special which is vintage style trem.
As far as the MiM Standard goes, there is only 21 frets instead of 22 of the American counterpart.
Not sure if you are looking at new or use but the new Japan made are really just the Pawn Shop series and some Mustang.
Also, the electronics on the American series are quite different. The Am. Special has Greasebucket tone circuit vs. No-Load Tone Control on the American Standard.