Re: anyone use cubase and guitar rig here?
Ok, something you might want to check is, to go up to the toolbar at the top and go: devices>VST connections. Then add a buss to the input and output tab, and make sure it is connected to your gear (it will make sense once you are there). Also, make sure you monitors/headphones or whatever are plugged into your interface. Most interfaces override the PC soundcard IIRC.
EDIT: One thing I have never like about cubase is for the simplest features, they are "buried hidden features" that you need to go through a million menus to get. If you get too frustrated, do yourself a favor, and at least try reaper. :shrug: