Yes and no.
Famous players develop their pickups along with their rigs.
If crunchlab/liquifire were developed to match Mark V then YES this new one is a marketing thing if not, it'll sound different than them IF people use Mark V but the majority use modellers and those pups weren't developed to match modellers.
They were developed to give a sound Petrucci likes, not to "match" a certain amp. He uses a large selection of Mesas - the V, certainly, but also Rectos, Stilettos, Lone Stars, IIC+s, and I think he's used a Transatlantic a bit lately. He also, incidently, had his Mesa rigs tone-matched in his AxeFX II and occasionally uses just that for smaller gigs, so they DO work with modelers.
Finding the right pickups for you
is a matter of finding something that both sounds and, arguably most importantly, feels
right through your amp and given the way you play. It may be a signature pickup (and one of my guitars has an AT1 in the bridge, which works beautifully for me because I play Mesas and dial them in fairly similar to Timmons and go after a similar sort of tone), it may not, but ultimately who's name is on it doesn't hugely matter as long as running through your rig it gives you the sound you want it to and responds well to your touch. It's unfortunately all a matter of trial and error, though to be fair knowing that you like similar gear and similar tones to an artist can help speed the search somewhat.