I would pick Breed before Super Distortion any day, in any guitar.
To be honest, I would pick Breed before any other pickup out there in most guitars.
Breed and SD are completely different pickups, and I just like the Breed best.
Breed is less hot, more dynamic. Breed also has a very nice spilt tone (and the neck version an amazing parallell tone).
Warmer and less aggressive metalsounding.
A rounder and fatter tone without being muddy, it just sings more in my ears.
More fusion then metal.